Offering a restaurant and luggage storage, the 3-star smoke-free Hotel Sereno Sestri Levante is around a 5-minute stroll from the Salita Mandrella. Located within a few blocks of the Renaissance church "Basilica di Santa Maria di Nazareth", this Sestri Levante hotel features a safe deposit box.

The hotel is near a boat dock and only 150 metres from the Via XXV Aprile. Immacolata Church stands within easy reach of the Sereno Sestri Levante. Nature lovers will appreciate the proximity to Spiaggia di Portobello, which is merely an 8-minute stroll away. The charming Spiaggia Baia del Silenzio Sandy Beach also lies just 1.1 km away. For those travelling from afar, Cristoforo Colombo airport is 51 minutes' drive away.

Hotel Sereno has 11 rooms, comprising an adjoining terrace and a balcony. A flat-screen TV with satellite channels, along with a mini fridge bar, are offered. Climate control are featured for guests' comfort. Offering such amenities as a hairdryer and a shower cap, the bathrooms also include a bidet, a separate toilet, and a shower.

Drinks are available at the lounge bar. The bar area includes a lounge. While staying at the Sereno, guests can choose from dining options nearby, such as Pak Kebab, located a mere 550 metres away, or I Due Forni Pizzeria at a 6-minute walking distance.