New Moon Prione Hotel La Spezia is situated right in the centre of La Spezia nearly a 5-minute walk from Saint George's Historic Castle. The guest house also includes a car park.

The Piazzetta del Bastione is a mere 300 metres away, while La Spezia Centrale train station is not far from the hotel. Guests can visit the "U. Formentini" Civic Museum, which is approximately a 10-minute walk away, and the Technical Naval Museum at La Spezia which is merely 0.6 km from the New Moon Prione. There is the Parco XXV Aprile 15 minutes away by car, and Stazione FS bus station is a short way from the property.

The air-conditioned rooms are fitted with climate control, as well as modern facilities like free wireless internet and a flat screen TV. There is also a private bathroom.

Guests may find the seafood restaurant Locanda del Mercato in close proximity to New Moon Prione Hotel.