Located 2.1 km from the Aquarium of Genoa, the recently renovated Exclusive Tra Mare E Centro Hotel Genoa is merely 6 minutes' walk from the performing arts theater "Teatro della Gioventu". The 4-star hotel also provides guests with a safety deposit box.

The guest house is near a train station and near the Foce. The Porto Antico is 2.2 km from the Exclusive Tra Mare E Centro Genoa, and Cristoforo Colombo airport is 5 km away. The Basilica of Santa Maria di Castello is nearly 25 minutes' walk away, while Brignole underground station is within reach of the property. This Genoa hotel is 550 metres from ATP bus station.

The rooms comprise a seating area and a dining area complete with an iron and ironing board, and an air conditioner, as well as a flat-screen TV with satellite channels. They are furnished with sound-proof windows, and also come with tea and coffee-making facilities. A bidet, a separate toilet, and a shower, along with free toiletries and a shower cap, are featured.

Exclusive Tra Mare E Centro Hotel is in close proximity to Le Cicale in Trattoria serving Northern-Italian dishes.