Located a 10-minute drive from the Sanctuary of the Madonna del Monte, Casa Rame Hotel Genoa is within 300 metres of the Basilica of the Most Holy Annunciation of the Vastato. This hotel also includes a car park.

Situated right in the centre of Genoa, the 3-star guest house is within easy reach of the Aquarium of Genoa. The Casa Rame is nestled a 5-minute walk from the black- & -white-striped Romanesque Genoa Cathedral. There is the central Genova Piazza Principe Railway Station 1.5 km away, and Genoa City Tour bus station is right around the corner from this property. The nearest underground station is Darsena, located a 5-minute walk away.

Some rooms include an ironing set and air conditioning, as well as coffee and tea makers for guests' utmost comfort. Furnished with a writing table, these rooms have a balcony and a terrace. Providing a bidet and a shower, some bathrooms are also equipped with bathrobes.

The restaurant Eataly Genova is situated within a 600-metre distance of Casa Rame Hotel.