The 3-star modern Hotel Acquario Genoa is situated only 550 metres from the opulent Royal Palace Museum and features 24-hour front desk assistance and express check-out. This Genoa hotel is in Genoa Historical Centre, which brims with traditional street food eateries, within a few blocks of such natural sights as the Villetta Di Negro.

The Palazzo della Borsa is just 0.8 km from the hotel, while the Palazzo Bianco is merely a 5-minute walk away. In the vicinity of the Acquario Genoa, business travellers will find the Embriaci Tower. Guests might as well visit Giardini Jack Clerici, which is 0.8 km away. The accommodation is situated within 15 minutes' walk of the Via XX Settembre, and Genoa City Tour bus station lies a mere 200 metres away. Hotel Acquario stands 250 m from Darsena tube station and in proximity to Genova Brignole train station.

The air-conditioned rooms at this Genoa hotel are furnished with wardrobes and a writing table and feature a minibar. The bedrooms come with small double beds. The private bathrooms provide guests with a bidet, a separate toilet, and a shower along with a hair dryer and towels.

An Italian breakfast is offered in the reception area. Drinks are available at the lobby bar. The bar area includes a lounge. In close proximity to the Acquario, Soho serves Italian meals.